← brief for 2026-09-30 · Slowing decline

Trained Immunity as a Mechanistic Bridge Between Uremic Toxins, Atherosclerosis, and Vascular Calcification in Chronic Kidney Disease.

Key takeaways

This review explains how toxins build up in the blood during kidney disease. It links these toxins to hardening of the arteries. It does not report new trial results. It helps explain why heart disease is common in kidney patients.

Who did this work

Zhang J · Chen Y · Tao S · Zhou M · Li C · Rao L · He Y · Chen Z

Source

Paper · PubMed, CKD severity and reversal · 2026 Sep 30
https://pubmed.ncbi.nlm.nih.gov/42814272/