← brief for 2026-09-30 · Slowing decline

The Binding of Fibroblast Growth Factor 23 (FGF23) to FGF Receptor-αKlotho Complex Increases Sinoatrial Electrical Activity.

Key takeaways

This study looked at a protein called FGF23 in the heart. It tested how this protein affects the heart's electrical signals. The work was done in mouse cells, not in people yet. It suggests this protein might play a role in heart rhythm issues.

Who did this work

Bertoli G (The Cell Physiology MiLab, Department of Biosciences, Università Degli Studi di Milano, Milan, Italy.) · Benzoni P (The Cell Physiology MiLab, Department of Biosciences, Università Degli Studi di Milano, Milan, Italy.) · Canzolino S (The Cell Physiology MiLab, Department of Biosciences, Università Degli Studi di Milano, Milan, Italy.) · Molla D (The Cell Physiology MiLab, Department of Biosciences, Università Degli Studi di Milano, Milan, Italy.) · Milanesi R (The Cell Physiology MiLab, Department of Biosciences, Università Degli Studi di Milano, Milan, Italy.) · Piantoni C (The Cell Physiology MiLab, Department of Biosciences, Università Degli Studi di Milano, Milan, Italy.) · Kuro-O M (Division of Mineral Metabolism, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan.) · Delgado C (Instituto de Investigaciones Biomédicas Sols-Morreale (CSIC-UAM), Madrid, Spain.) · Ruiz-Hurtado G (Cardiorenal Translational Laboratory, Imas12 Research Institute, Hospital Universitario 12 de Octubre, Madrid, Spain.) · Baruscotti M (The Cell Physiology MiLab, Department of Biosciences, Università Degli Studi di Milano, Milan, Italy.) · Bucchi A (The Cell Physiology MiLab, Department of Biosciences, Università Degli Studi di Milano, Milan, Italy.)

Source

Article · Europe PMC, CKD · 2026-10-01
https://doi.org/10.1111/apha.70293