← brief for 2026-09-30 · Transplant & xeno

Apixaban Use Before Kidney Transplantation: Is Reversal Necessary?

Key takeaways

This study looked at people taking a blood thinner called apixaban before a kidney transplant. It checked if they needed a special drug to stop the blood thinner before surgery. The team found that skipping this reversal drug did not cause more bleeding after the operation. This is an observational study, so it shows a link but not proof of cause.

Who did this work

Cotiguala L (Edward Hines Jr. VA Hospital, Hines, Illinois, USA.) · Przybylski A (Edward Hines Jr. VA Hospital, Hines, Illinois, USA.) · Linberger L (Rush University Medical Center, Chicago, Illinois, USA.) · Brokhof M (Rush University Medical Center, Chicago, Illinois, USA.) · Kenyon N (Rush University Medical Center, Chicago, Illinois, USA.) · Joyce C (Loyola University Medical Center, Maywood, Illinois, USA.) · Dierker M (Edward Hines Jr. VA Hospital, Hines, Illinois, USA.) · Ferguson K (Edward Hines Jr. VA Hospital, Hines, Illinois, USA.) · Rech MA (Department of Veterans Affairs, Center of Innovation for Complex Chronic Healthcare, Edward Hines, Jr. VA Hospital, Hines, Illinois, USA.) · Trotter C (Edward Hines Jr. VA Hospital, Hines, Illinois, USA.) · Aguirre O (Edward Hines Jr. VA Hospital, Hines, Illinois, USA.) · Lopez-Soler RI (Edward Hines Jr. VA Hospital, Hines, Illinois, USA.)

Source

Article · Europe PMC, CKD · 2026-10-01
https://doi.org/10.1002/phar.70200