← brief for 2026-09-29 · Slowing decline
Effects of Lithium Treatment on Renal Function in Bipolar Disorder: A Retrospective Cohort Study.
Key takeaways
This study looked at 636 people with bipolar disorder who took lithium for at least one year. It found a link between long-term lithium use and a drop in kidney function. This is an observational study, so it shows a connection but not proof that the drug causes the decline. The data comes from a single clinic between 2010 and 2022.
Who did this work
İnanlı İ · Ayhan MG · Yıldız L · Mert M · Yıldız N
Source
Article · PubMed, CKD progression and prevention · 2026 Sep 24
https://pubmed.ncbi.nlm.nih.gov/42810282/