Kidney research, 2026-09-29
Long-term lithium use is linked to a drop in kidney function.
The main news today is a link between long-term lithium use and kidney decline. This is an observational study, so it shows a connection but not proof that the drug causes the change. Other reports covered food toxins and a new leg procedure. The lithium finding is important for anyone taking that medication.
Spatially resolved transcriptomics of glomerular diseases
This is a preprint that uses a new technology to map kidney disease. It looks at 59 people to find common patterns in how kidneys fail. It has not passed peer review yet.
Targeting tubular NAT10 ameliorates the renal Tubulointerstitial Fibrosis in Obstructive and Folic Acid-Induced Nephropathy.
This study looked at a protein called NAT10 in kidney cells and animals. It found that blocking this protein reduced scarring in the kidney tissue. This work was done in the lab,...
BOLALAR GEMODIALIZ BEMORLARIDA ANEMIYANI DAVOLASH SAMARADORLIGINI BAHOLASH VA ESA GA JAVOBNI PROGNOZLASH
This review looks at treating low blood count in children on dialysis. It discusses how to use iron and other drugs. It is a summary of existing guidelines, not a new trial with...
What is the guidance on maintenance dosing of oral paliperidone in adults with renal failure or acute kidney injury?
This note looks at how to dose a specific drug for people with kidney failure. It says doctors must adjust the dose based on kidney function. It is a guidance summary, not a new...
PATHOMORPHOLOGICAL CHANGES IN THE KIDNEYS IN DIABETES MELLITUS
This article explains how high blood sugar from diabetes damages kidneys. It describes how the tiny filters and blood vessels get scarred. It is a background review, not a new...
Efficacy and Safety of Incremental Hemodialysis: A Systematic Review and Meta‐Analysis
This review combined many studies to check if starting dialysis slowly is safe. It found that a slower start may help keep some kidney function and improve quality of life. It also...
HIV-associated nephropathy: A decade of clinical outcomes, global disparities and emerging promise.
This review summarizes what is known about kidney disease caused by HIV. It covers how the disease works and how it is treated. It is a narrative review, so it does not report new...
Identification and validation of a chronic kidney disease prediction model after radical nephrectomy: a multicenter cohort retrospective study.
This study built a tool to predict kidney decline in 649 people who had a kidney removed. It tested the tool on patients from eight different centers. This is an observational...
Urogenital Infection Risk Associated With SGLT2 Inhibitors Versus DPP-4 Inhibitors in Type 2 Diabetes and Chronic Kidney Disease: A Nationwide Target Trial Emulation.
This study used health records from Korea to check if a common kidney drug causes more urinary tract infections. It compared people who started this drug with people who took a...
Potential bone marrow-driven reduction of circulating inflammatory monocytes by semaglutide in Type 2 diabetes.
This small study looked at 16 people with type 2 diabetes who took a drug called semaglutide. The researchers found that the drug lowered the number of certain immune cells in the...
Pharmacological interventions for vascular calcification in chronic kidney disease: A systematic review and meta-analysis of randomized controlled trials.
This review looked at many studies on drugs for hardening of the arteries in kidney disease. It found that no single drug has been proven to stop this hardening yet. This is a...
Telemonitoring of Hypertensive Patients With Chronic Kidney Disease
This is a study that is starting or planned. It will check if remote blood pressure monitoring helps people with kidney disease. There are no results yet.
Sarcopenia among chronic kidney disease patients attending a renal clinic in Northwest Ethiopia: a cross-sectional study of prevalence, risk factors and clinical implications.
This study looked at kidney patients in Ethiopia. It checked how many had muscle loss, a condition called sarcopenia. It shows a link between kidney disease and muscle loss, not...
High complement activation index predicts renal progression in crescentic IgA nephropathy
This study looks at a blood test for a type of kidney disease called IgA nephropathy. It checks if a high score predicts that the kidneys will get worse. There is no abstract, so...
Case Report: A rare complication easily misdiagnosed as bacterial peritonitis: a case of sterile peritoneal dialysis-chemical peritonitis induced by amino-acid-based dialysate and literature review
This is a report on one person who had a rare reaction to dialysis fluid. It is not a large study. There is no abstract, so we do not have the full details yet.
Transcriptomics- and machine learning-based identification and mechanistic in vitro validation of a cardiovascular risk gene signature at the CKD–cancer intersection: a multi-omics approach
This study uses computer tools to look at genes in people with both kidney disease and cancer. It is a complex lab study. There is no abstract, so we do not have the results yet.
Study variation in estimating Glomerular Filtration Rate (GFR) from serum creatinine, cystatin C, age, and sex
This study looked at how well standard blood tests predict kidney function. It used data from 13,391 people across 26 studies. The researchers found that results can vary depending...
Atypical Renal Hypoplasia in HNF1B-Related Disease: The Clinical Impact of Early Genetic Diagnosis
This is a report on one 28-year-old woman with a rare genetic kidney condition. Her kidneys were small and lacked the usual cysts. The report highlights how early genetic testing...
Hubungan Kadar Hemoglobin dengan Derajat Anemia Pada Pasien Penyakit Ginjal Kronik Berdasarkan Rekam Medis di Rs Royal Prima
This study checked medical records for 93 people on dialysis. It looked at the link between blood count levels and the severity of anemia. The data shows a connection between these...
Prediagnostic plasma proteomic signatures associated with incident chronic kidney disease in type 2 diabetes
Researchers followed 1,715 adults with type 2 diabetes for an average of 14.6 years. They found that certain proteins in the blood can signal future kidney damage. This shows a...
Association of the CIMI with multimorbidity classification among U.S. adults with CKD and cancer via interpretable SHAP-based machine learning
This study used computer models to look at people with both kidney disease and cancer. It found that certain blood test scores can help identify these patients. This shows a link...
Nutrient-Sensitive Senescence Checkpoints in Diabetic Kidney Disease
This article explains how aging cells in the kidney react to high blood sugar. It describes how these cells make decisions about repair and damage. There are no new test results in...
Potential anti-inflammatory effect of L-carvone in endothelial dysfunction triggered by uremia related to chronic kidney disease
Researchers tested a plant compound called L-carvone on human blood vessel cells in a lab. The cells were exposed to blood from people on dialysis. The compound helped calm...
Differential impact of chronic kidney disease on the risk of ischemic versus hemorrhagic stroke: a nationwide population-based cohort study
This huge study followed nearly 10 million adults for ten years. It found that kidney disease raises the risk of both types of stroke. It shows a strong link, but it does not prove...
Hemodialysis-Associated Asymmetry in Serum Zinc Concentrations Measured by ICP-MS: A Paired Observational Clinical Study
This study measured zinc levels in 40 people before and after dialysis. It found that zinc levels changed during the treatment. This shows a link between dialysis and zinc shifts,...
Early-Life Oxidative Stress and Pediatric Kidney Disease: From Developmental Programming to Preventive Strategies
This review looks at how stress on a baby's kidneys in the first year of life might affect health later. It discusses factors like prematurity and maternal health. There are no new...
Safety and Efficacy of Finerenone in Diabetic Kidney Disease: A Single-Center Retrospective Real-World Comparative Study of Dosing and Clinical Decision-Making in Taiwan
This study compared 100 people with diabetic kidney disease. Half took a drug called finerenone, and half did not. The drug group had less protein in their urine. This is an...
Vascular access options for complex high-risk indicated percutaneous coronary interventions: contemporary strategies, trade-offs, and practical algorithms
This review discusses how doctors choose where to enter the body for heart procedures. It notes that many of these patients also have kidney disease. There are no new test results...
Metabolic control by liver–kidney crosstalk and glucagon in health and disease
This review explains how the liver and kidneys talk to each other. It focuses on a hormone called glucagon. It describes how these organs work together in health and disease.
Estimating the Wider Societal Impact of Semaglutide Across Multiple Indications in Canada: an Economic Evaluation.
This study looks at the cost and benefits of a diabetes drug called semaglutide. It estimates how the drug affects society in Canada over five years. It is an economic model, not a...
Aortic Reoperation and Late Survival Following Repair of Acute Type A Dissection.
This study followed 668 people who had heart surgery for a torn aorta. It looked at how blood pressure control affected their long-term survival. The study found that good blood...
One year outcomes of Percutaneous Deep Vein Arterialization in the Dutch LimFlow Registry.
This study looked at 23 people with severe leg blood flow issues. They had a new procedure to improve blood flow. The study reports on their outcomes after one year. It is a small...
Effects of Lithium Treatment on Renal Function in Bipolar Disorder: A Retrospective Cohort Study.
This study looked at 636 people with bipolar disorder who took lithium for at least one year. It found a link between long-term lithium use and a drop in kidney function. This is...
Lifestyle Narrowing in Chronic Kidney Disease: The Hidden Burden of Incremental Symptom Accumulation.
This article discusses how symptoms build up in people with kidney disease. It has no abstract, so no specific results are available yet.
Comparative Renal Effectiveness of GLP-1RA and SGLT2i in US Veterans with Type 2 Diabetes and CKD.
This study compared two diabetes drugs in older veterans with kidney disease. It looked at a large group to see which protected kidneys better. It shows a link, not proof of cause.
Chilean Multidisciplinary Consensus on the Use of GLP-1 Receptor Agonists: Recommendations Based on the GRADE Methodology.
This is a set of guidelines for doctors in Chile. It recommends how to use GLP-1 drugs for diabetes and kidney disease. It is a consensus statement, not a new trial.
Hubungan Kadar Glukosa Darah, Albumin dan Kreatinin Pada Penyembuhan Luka Pasien Diabetes Melitus
This study checked if blood sugar and protein levels affect how fast wounds heal in people with diabetes. It shows a link between these levels and healing, but it is not proof of...
Prevalence and Overlap of Malnutrition, Sarcopenia and Related Nutritional Syndromes in a Large Haemodialysis Population.
This large study checked 40 dialysis clinics in Saudi Arabia. It found that many people on dialysis are at risk for muscle loss and poor nutrition. The study shows a link between...
Pengaruh Pemberian Virgin Coconut Oil Terhadap Kelembapan Kulit Pada Pasien Gagal Ginjal Kronik (GGK) yang Menjalani Hemodialisis
People on dialysis often have very dry skin. This study looked at whether applying virgin coconut oil helped. It used a small group of patients and measured skin moisture before...
Vaccines and Kidney Disease
This video from the National Kidney Foundation talks about getting vaccines. It explains why people with kidney disease should protect themselves from infections. There are no new...
The Role of Traditional Chinese Medicine in the Treatment of Lupus Nephritis.
This review discusses how Traditional Chinese Medicine is used to treat lupus nephritis. It explains the theory behind the treatment and how it fits with standard care. There are...
Systematic review and meta-analysis of adverse health effects associated with mycotoxin exposure.
This large review combined data from many studies on mycotoxins. These are toxic substances from mold that can be in food. The review looks at how these toxins affect human health....
Cross-Talk Between Sleep Quality and HRQoL in CKD: Insights from Network and Cost–Utility Analysis
This study looks at how sleep quality affects the quality of life for people with chronic kidney disease. It is a preprint, so it has not yet passed peer review. There are no...
Effectiveness and Safety of Virtual Reality Interventions for Symptom Management in Adults Undergoing Hemodialysis: Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This review looked at many studies to see if virtual reality helps people on dialysis. It found that VR can ease symptoms and improve the treatment experience. This is a strong...
Factors Associated with Depression and Anxiety Among Patients with Chronic Kidney Disease: A Cross-Sectional Study at Bagalkot, Karnataka.
This study looked at people with chronic kidney disease in a specific region of India. It checked how many had depression or anxiety. The results show a link between kidney disease...
Hubungan Lama Hemodialisa dan Tingkat Stres dengan Tingkat Kecemasan pada Pasien Gagal Ginjal Kronis di Rumah Sakit Bhayangkara Makassar
This study surveyed 56 people on dialysis about their stress and anxiety. It found a link between how long they had been on treatment and their stress levels. This shows a...
Evaluation of Multiple Administrations of Amniotic Membrane-derived Mesenchymal Stem Cells in a Cat with Acute-on-chronic Kidney Disease: A Case Report
A 17-year-old cat with kidney disease was treated with stem cells. The cat got nine doses of these cells over time. It stayed stable during the treatment. This was in an animal,...
Deep learning–based clinical decision support for renal cell carcinoma using computed tomography: an expert-informed scoping review
This review looks at how computer programs can help doctors spot kidney cancer on scans. It is a scoping review, which maps out what is known. The record does not include the...
Machine Learning-assisted in Silico Analysis Identifies Shared Proteomic Signatures Between Chronic Kidney Disease and Renal Cell Carcinoma
This research used computer models to find shared protein patterns between kidney disease and kidney cancer. It is a computer-based analysis, not a test on people. The record does...
Artificial Intelligence-Guided Extracellular Vesicle Platforms for Diagnosis and Treatment of Chronic Kidney Disease: A Scoping Review and Future Directions
This review maps out how AI and tiny cell particles might help diagnose and treat kidney disease. It summarizes current research but does not report new clinical trial results. It...
Living‐Donor Kidney Transplantation From an Attained Identical Twin Donor Status After Prior Hemopoietic Cell Transplantation
This report describes a rare case of a kidney transplant from an identical twin. The donor had previously received a bone marrow transplant. Because the record has no abstract, we...
The Asian perspective on xenotransplantation: bridging the organ gap through regional collaboration and tailored clinical protocols.
This review discusses how Asian countries are working together to use pig organs for transplants. It looks at rules and culture. There are no results yet.
Complement system in kidney transplantation: from innate immune surveillance to a therapeutic and genetic engineering target
This review explains how the body's immune system affects kidney transplants. It discusses how this system can cause rejection and how new drugs might help. It is a summary of...
Tubal fimbria encapsulation of peritoneal dialysis catheter diagnosed by laparoscopy: a case report and literature review
This is a report on one patient whose dialysis tube got blocked by a part of her reproductive system. Doctors used a camera to see the problem and fix it. It is a single case, not...
Perioperative Rhabdomyolysis Following Prolonged Laparoscopic Radical Nephrectomy in the Lateral Decubitus Position
This is a case report about a patient who had muscle breakdown after kidney surgery. The muscle breakdown can hurt the kidneys. It is one person's experience, not a large study...
Validity and reliability of the indonesian version of the kidney health literacy instrument for adolescents
This study checked if a survey works well for teens in Indonesia. It tests if the questions measure kidney knowledge correctly. It is a tool check, not a treatment trial, so there...
Identification of holistic needs in people with chronic kidney disease
This review looks at how doctors can check the full needs of people with kidney disease. It covers physical, mental, and social needs, not just kidney function. The paper lists...
Tren Penelitian Self Management pada Chronic Kidney Disease (Ckd) : Analisis Bibliometrik
This study maps out research trends on self-management for kidney disease. It looks at what topics are being studied and by whom. It is a bibliometric analysis, which counts and...
Comparison of vascular access outcomes in octogenarian patients undergoing hemodialysis
This study looked at 266 people over age 80 who needed dialysis. It compared two types of blood vessel connections. It shows a link between the type of connection and how well it...
The population frequency of predicted pathogenic variants in the genes associated with Autosomal Dominant Polycystic Liver Disease (ADPLD) and kidney cysts
This study checked how common certain gene changes are in the general population. These genes are linked to liver and kidney cysts. It used a large database of genetic information....
Serum electrolyte disturbances in patients with chronic kidney disease compared with healthy controls: A hospital-based study from District Swabi, Pakistan
This study compared blood salt levels in people with kidney disease and healthy people. It took place in a hospital in Pakistan. The record does not include the study's findings.
Association Between Estimated Glomerular Filtration Rate and the Number of Remaining Teeth Among Korean Adults: Analysis of the Ninth Korea National Health and Nutrition Examination Survey, 2022–2024
This study checked if kidney function is linked to the number of teeth a person has. It used data from a large health survey in Korea. The record does not include the study's...
https://www.theisn.org/blog/event/isn-webinar-dialysis-or-conservative-kidney-management-for-kidney-failure-the-first-results-of-the-prepare-for-kidney-care-randomized-controlled-trial/
This is a page for a webinar about a study on kidney failure. The study looks at whether dialysis or a different care plan is better. There are no results from the study yet, only...
The Epidemiological Profile of Non-Communicable Diseases in Jamaica: Burden, Transition, Social Patterning, Risk Factors, Health-System Challenges, and Priorities for Prevention and Control
This report looks at the health of people in Jamaica. It covers many diseases, including kidney disease. It describes how common these diseases are and what causes them. This is an...
Routine Distributional Analysis of Health Inequality Impact by Socioeconomic Group: Technical Feasibility Study in Queensland, Australia
This study tests a tool that measures how healthcare affects people of different income levels. It focuses on the technical setup of the tool in Australia. It does not report on...