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Development of a monoclonal antibody targeting the calcification blocking factor CBF

Article D Peer reviewed Preclinical

Key takeaways

Researchers built a new test to measure a protein called CBF. This protein helps stop blood vessels from hardening, which is a common problem in kidney disease. The study focused on making the test fast and easy to use. It was done in the lab, not in people yet.

Who did this work

Dustin Mikolajetz (RWTH Aachen University) · Zhuojun Wu (RWTH Aachen University) · Caron Romel (Universitätsklinikum Aachen) · Emiel P. C. van der Vorst · Heidi Noels (Maastricht University) · Leon J. Schurgers (Maastricht University) · Peter W. de Leeuw · Abraham A. Kroon (Maastricht University Medical Centre) · Turgay Saritas (Erasmus MC) · Julia Moellmann (Universitätsklinikum Aachen) · Matthias Rau (Universitätsklinikum Aachen) · Michael Lehrke (Universitätsklinikum Aachen)

Source

Article · OpenAlex, CKD works · 2026-09-27
https://doi.org/10.1016/j.biopha.2026.119958