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← brief for 2026-09-28 · Regeneration & devices

CAR T cell targeting of inflammatory myeloid progenitors in the bone marrow remodels border-associated macrophages and reverses cognitive aging

Preprint D Not peer reviewed Preclinical

Key takeaways

This research used a type of cell therapy in mice to treat brain aging. The therapy helped restore memory and thinking skills in the animals. This work was done in mice, not people, so it is not ready for human use yet. It offers a new idea for treating brain changes linked to aging.

Source

Preprint · bioRxiv cell biology (kidney-filtered downstream) · 2026-09-28
https://www.biorxiv.org/content/10.64898/2026.09.27.754777v1?rss=1