Kidney research, 2026-09-27

Lupus nephritis at systemic lupus erythematosus onset and kidney outcomes in a Latin American biopsy-proven cohort.

This study looked at people with lupus who also had kidney damage. It checked if having kidney damage at the start of lupus affects long-term health. The study found a link between...

When the Gallbladder Hurts the Thigh: Silent Gallbladder Empyema With Perforation Presenting as Severe Rhabdomyolysis

This report describes one 71-year-old man with kidney disease and diabetes. He had a severe gallbladder infection that caused muscle breakdown. The case shows how a common...

Unmet Needs in the Management of Adult Patients with Lupus Nephritis.

This article discusses the challenges of treating lupus nephritis. It notes that many patients still progress to kidney failure. It highlights issues with current treatments and...

Sudomotor dysfunction is associated with loss of residual renal function in patients undergoing peritoneal dialysis.

This study checked nerve function in 86 people on peritoneal dialysis. It found a link between nerve issues and the loss of remaining kidney function. The study shows a connection,...

Time to diagnosis of acute kidney injury and its predictors among outborn neonates in India: a competing-risk analysis of tele-ICU network data (2022-2024).

This study tracked newborns in India who were born outside the hospital. It looked at how long it took to diagnose sudden kidney injury. The data came from 27 sites over two years....

Obesity and chronic kidney disease: a cardio-kidney-metabolic framework for renal vulnerability and risk stratification.

This review explains how obesity can hurt the kidneys. It uses a new framework that looks at the heart, kidneys, and metabolism together. The authors suggest that weight alone is...

Rituximab for relapsing nephrotic syndrome in adults: closing the evidence gap

This is a review of studies on a drug called rituximab. It looks at how well the drug works for a kidney condition. There are no new results in this piece. It summarizes what is...

Lupus podocytopathy with focal segmental glomerulosclerosis pattern and anti-neutrophil cytoplasmic antibody positivity: a case report

This is a report on one person with a rare kidney condition. It describes her symptoms and test results. It is a single case, so it does not show what happens to many people. It...

Platinum-based chemotherapy and nephrotoxicity: frequency, clinical characteristics and outcomes in a mexican tertiary-centre cohort

This study looked at people in Mexico who got a type of cancer drug. It found that these drugs often cause kidney injury. This shows a link between the drug and kidney damage, but...

Semaglutide and Tirzepatide in Cardiovascular and Cardiometabolic Risk Management: Evidence Maturity, Patient Selection, and Real-World Implementation

Protective Effects of 2-Chloro-3-Hydrazinylquinoxaline against Doxorubicin-induced Nephrotoxicity via Modulation of Oxidative Stress and Inflammation in Rats

This study used 30 rats to test a chemical called CHQ. The rats were given a cancer drug that often hurts the kidneys. The chemical seemed to protect the kidneys from this damage....

SGLT2 Inhibitors Beyond Glycemic Control: Emerging Pharmacological and Cardiovascular Applications A Narrative Review

This review explains how SGLT2 inhibitors work. These drugs were made to lower blood sugar, but they also protect the heart and kidneys. The text says they can slow kidney disease...

Birth Weight Associated With Kidney Size in Middle-Aged Women

Association of FTO (rs9940128) Gene Polymorphism in Type 2 Diabetes Mellitus with Chronic Nephropathy in North Indian Population

This study looked at 110 people with diabetes and 110 without. It checked for a specific gene change linked to obesity and kidney disease. The study found a link between the gene...

Integrated Cardiorenal Risk in Multimorbidity: Emerging Biomarkers, Prognostic Stratification, and Contemporary Therapeutic Strategies

This article reviews how heart and kidney problems often affect each other. It focuses on people who have several health issues at once, like diabetes or high blood pressure. The...

How to treat drug-induced hypotension that exacerbates chronic kidney disease?

This piece discusses a drug called Angiotensin II acetate. It is used to treat very low blood pressure caused by other medicines. The text notes this is helpful for people with...

Association of finerenone with graded proteinuria improvement in type 2 diabetes with chronic kidney disease and proteinuria >1 g/d: a retrospective cohort study.

This study looked at people with diabetes and kidney disease. It checked if a drug called finerenone reduced protein in the urine. The study found a link between the drug and less...

Mechanism of SGLT2 inhibitors in improving immune imbalance in diabetic mice with sepsis via regulating macrophage M2 polarization through the APOC1/HMGB1/TLR4 axis.

This study looked at mice with diabetes and a severe infection. It tested how a diabetes drug affects the immune system. The drug helped balance the immune response. This was done...

Dapagliflozin Attenuates NKCC2 Protein Expression and Alleviates Diabetic Kidney Disease in Salt Loaded-Hypertensive Diabetic Db/Db Mice.

This study used mice with diabetes and high blood pressure. It tested a drug called dapagliflozin. The drug helped the mice's kidneys. This was done in animals, not people yet.

Longitudinal impact of sodium bicarbonate therapy on health-related quality of life in pre-dialysis chronic kidney disease with metabolic acidosis: a pragmatic trial in Malaysia.

This trial followed 74 people with stage 3 and 4 kidney disease for 18 months. It found that taking a bicarbonate drink improved their daily well-being. The study was small, so the...

Association between ABCG2 transporter functionality and CKD progression: a retrospective cohort study in patients with CKD stage G3.

This study looked at 317 people with stage 3 kidney disease. It checked if a specific gene affects how fast the kidneys decline. This is an observational study, so it shows a link,...

Associations Between Kidney Function and Risk of Cognitive Impairment Among Chinese Older Adults.

This study followed older adults in China to see if kidney health links to brain health. It found that people with lower kidney function had a higher risk of memory problems. This...

Feasibility of the Comprehensive Overweight/Obesity Management Pre-Kidney Transplant Program: A Group-Based Lifestyle Intervention and GLP-1 Receptor Agonist Therapy for End-Stage Kidney Disease Candidates Ineligible Due to Obesity.

This study tested a weight loss program for people waiting for a kidney transplant. It used group education and a type of diabetes drug. The study was small and focused on whether...

Unraveling the roles of anemia, renal impairment, and neuroinflammation in hemodialysis-associated cognitive dysfunction in chronic kidney disease patients

This study looked at people with kidney disease who are on dialysis. It found links between low blood counts, poor kidney function, and brain changes. These factors may explain why...

Prevention of radial artery occlusion with rivaroxaban after interventional coronary interventions using transradial access: Results of a single-center randomized clinical trial

This trial tested a blood thinner to protect the wrist artery. The artery is often used for dialysis access. The drug helped keep the artery open after a heart procedure. The study...

Supplemental Material For: Mesenchymal stromal cell derived membrane particles improve metabolic activity and functional performance during porcine kidney normothermic machine perfusion

This study used pig kidneys to test a new treatment. Researchers added particles from stem cells to the kidneys during a machine perfusion process. The treatment helped the kidneys...

Residual hydronephrosis after paediatric pyeloplasty: longitudinal APD reference curves

T-Cell Remodeling in Renal Fibrosis: From Acute Injury to Chronic Kidney Disease.

This review summarizes how immune cells affect kidney scarring. It explains the process from early injury to long-term disease. It is a summary of existing research, not a new...

Transplant and immunosuppression eligibility restrictions in phase III systemic-therapy trials for renal cell and urothelial carcinoma: a registry–protocol meta-research study

This study looks at cancer trial rules. It checks if people with transplants are allowed to join. There are no new results on how the drugs work. It is a look at who is allowed in...

Association of Eplet Mismatch Load and Allograft Injury in Kidney Transplant Recipients

This study looked at 657 people who received a kidney transplant. It checked how well the donor and recipient matched at a molecular level. The team found a link between a poor...

Should we use the SARC-F score in sarcopenia screening in kidney transplant patients?

Development of a structured shared decision-making model for implementation in hospital care

This study developed a model for shared decision-making in hospitals. It included patients with advanced kidney disease. It is a pilot study on care processes, not a test of a drug...