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Multi-omics integration identifies Acsm2/ACSM2A deficiency as a metabolic driver of ZBP1-mediated PANoptosis in acute kidney injury

Key takeaways

This study looked at how kidney cells die during sudden injury. It found that a lack of a specific enzyme can trigger a type of cell death. The research was done in mice and cells, not in people. It helps explain how sudden kidney damage can turn into long-term disease.

Who did this work

Lijuan Lu (Nantong University) · Yuping Qin (Nantong University)

Source

Article · OpenAlex, CKD works · 2026-09-23
https://doi.org/10.3389/fcell.2026.1936504