← brief for 2026-09-24 · Slowing decline

IL-17A Mediates Cardiac Hypertrophy in Chronic Kidney Disease through the IL-23/Th17 Axis.

Preprint D Not peer reviewed Preclinical

Key takeaways

This study used mice to look at how kidney disease affects the heart. It found that a specific immune signal may cause heart muscle to thicken. This was done in animals, not people yet.

Who did this work

Fumihiko Ogata (Kumamoto University) · Shinsuke Hanatani (Kumamoto University) · Yuki Okuno (Kumamoto University) · Masahiro Yamamoto (Kumamoto University) · Kei Morikawa (Kumamoto University) · Takumi Nagakura (Kumamoto University) · Satoshi Araki (Kumamoto University) · Eiichiro Yamamoto (Kumamoto University) · Yuichiro Arima (Kumamoto University) · Yasuhiro Izumiya (Kumamoto University) · Kenichi Tsujita (Kumamoto University)

Source

Preprint · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-09-23
https://doi.org/10.64898/2026.09.17.752355