← brief for 2026-09-24 · Slowing decline

FGF23 –Klotho Axis Dysregulation in Type 4 Cardiorenal Syndrome: Molecular Mechanisms, Paediatric Perspectives, and Emerging Therapeutic Targets

Key takeaways

This review explains how a hormone system called FGF23 affects the heart in children with long-term kidney disease. It looks at how this system breaks down and what new drugs might target it. There are no new trial results in this article.

Who did this work

Mohammed AbuBaha (An-Najah National University) · Samia Ammar Aldwaik (An-Najah National University) · Ahmad Nouri (An-Najah National University) · Anwar Zahran (An-Najah National University) · Bara Abubaha (An-Najah National University) · Ameer Awashra (An-Najah National University) · Sarah Saife (An-Najah National University) · Yousef I. Barqawi (An-Najah National University) · Duma Hamada · Abdalhakim R. M. Shubietah (An-Najah National University)

Source

Article · OpenAlex, CKD works · 2026-09-23
https://doi.org/10.1111/nep.70287