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← brief for 2026-09-23 · Slowing decline

Long-Term Renal Function and Clinical Outcomes of Sacubitril/Valsartan in HFrEF and Stage 3-4 Chronic Kidney Disease: A 24-Month Single-Centre Cohort.

Article C Peer reviewed Observational

Key takeaways

This study followed 360 people with heart failure and kidney disease for up to 24 months. It found that a drug called sacubitril/valsartan was safe and did not make kidney function worse. This is an observational study, so it shows a link, not proof of cause.

Who did this work

Akkaya F · Şeker OO · Türkmen E · Dereli S

Source

Article · PubMed, the drug frontier · 2026 Sep
https://pubmed.ncbi.nlm.nih.gov/42775828/