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GLP-1 receptor agonists and podocyte senescence in diabetic kidney disease: structural pharmacology, mechanistic evidence, and multi-receptor agonism.

Paper D Peer reviewed Preclinical

Key takeaways

This review explains how certain diabetes drugs affect kidney cells. It focuses on a process called cell aging, or senescence. The study looks at how the drugs bind to these cells in the lab. This is preclinical work, meaning it is not yet tested in people.

Who did this work

Yue H · Wang Y · Guo X · Sun Y · Cheng Y · Yan P · Tan Z · Han C · Wang B

Source

Paper · PubMed, the drug frontier · 2026 Sep 23
https://pubmed.ncbi.nlm.nih.gov/42777788/