← brief for 2026-09-23 · Slowing decline

Comparative Effectiveness of Once-Weekly Semaglutide Versus Sulfonylureas, DPP4 Inhibitors, and Thiazolidinediones in Patients with Type 2 Diabetes and Chronic Kidney Disease.

Article C Peer reviewed Observational

Key takeaways

This study compared a weekly diabetes shot called semaglutide with older pill-based drugs. It looked at real-world data from people with type 2 diabetes and kidney disease. The results suggest the weekly shot may be better for protecting kidneys. This is an observational study, so it shows a link but not proof of cause.

Who did this work

Amamoo J · Wang Y · Liu H · Sundar M · Song Y · Xie L · Mehanna S · Noone J · Swift C · Weir MR

Source

Article · PubMed, the drug frontier · 2026 Sep 23
https://pubmed.ncbi.nlm.nih.gov/42776473/