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Citrate-Dependent Activation of Acetyl CoA Carboxylase Promotes Renal Lipid Accumulation in a Rat Model of Chronic Kidney Disease.

Article D Peer reviewed Preclinical

Key takeaways

This study used rats and cells, not people. It found that a chemical called citrate can cause fat to build up in the kidney. This may help explain how kidney disease gets worse. It is early research, so it is not yet proven in humans.

Who did this work

Sanz-Gómez M · Linillos-Pradillo B · Fernández de la Rosa R · Aránguez I · Kreutz R · García A · Barbas C · Plaza A · Fernández-Alfonso MS

Source

Article · PubMed, CKD progression · 2026 May
https://pubmed.ncbi.nlm.nih.gov/42775821/