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Congenital Anomalies of the kidney and urinary tract: pediatric origins and adult outcomes

Key takeaways

This review covers kidney and urinary tract defects that babies are born with, called CAKUT. They make up 20% to 30% of all defects found before birth, and about 3.83 of every 1,000 babies have one. About one in five cases has a genetic cause, most often changes in genes called HNF1B and PAX2. The review draws on observational research, which shows links, not proof of cause, and it looks at how these childhood conditions affect kidney health in adults.

Source

Paper · Kidney International · 2026-09-22
https://www.kidney-international.org/article/S0085-2538(26)00797-0/fulltext?rss=yes