← brief for 2026-09-22 · Regeneration & devices

Kidney organoids as a platform to study plasminogen-induced injury and uPA-based therapies.

Key takeaways

Researchers used tiny lab-grown kidney models to study a protein that can damage kidneys. They tested a drug called amiloride to see if it could help. This was done in the lab, not in people yet. It helps us understand how to treat protein in the urine.

Who did this work

de Cos M · Yu SM · Wright J · Anandakrishnan N · Meliambro K · Wong JS · Azeloglu E · Campbell KN

Source

Article · PubMed, organoids & devices · 2026 Sep 18
https://pubmed.ncbi.nlm.nih.gov/42768826/