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High Serum Uric Acid Promotes Metastasis by Disrupting Endothelial Functions Through the NF-κB-NOX4 Pathway

Key takeaways

This study was done in cells, not in people yet. It found that high uric acid can help cancer spread. It does this by changing how blood vessel cells work.

Who did this work

Geonhui Lee (Johns Hopkins University) · Yebin Im (Johns Hopkins University) · Rodger Black (Johns Hopkins University) · Jasmine Kim (Johns Hopkins University) · Michaela Bhoorasingh (Johns Hopkins University) · Mallikarjun Reddy (Johns Hopkins University) · Sangmoo Jeong (Johns Hopkins University)

Source

Article · OpenAlex, CKD works · 2026-09-21
https://doi.org/10.1007/s12195-026-00943-9