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Resident immune cell neighborhoods associate with protein kinase pRIPK3 and fatty acid ligase FACL4 expression during cell injury in ANCA associated vasculitis and lupus nephritis

Paper C Peer reviewed Observational

Key takeaways

Researchers studied kidney tissue from people with two autoimmune kidney diseases: ANCA vasculitis and lupus nephritis. They found that clusters of immune cells sat near kidney cells showing signs of two cell-injury proteins, pRIPK3 and FACL4. This shows a link, not proof that these immune cells cause the damage. The part we have gives no patient numbers, and any new treatment target is still a future idea.

Source

Paper · Kidney International · 2026-09-15
https://www.kidney-international.org/article/S0085-2538(26)00738-6/fulltext?rss=yes