← brief for 2026-09-16 · Slowing decline

Therapeutic Modulation of Nitric Oxide Pathways to Address Insulin Resistance in Cardiovascular-Kidney-Metabolic Syndrome.

Article D Peer reviewed Preclinical

Key takeaways

This review explains how problems in the nitric oxide pathway may link insulin resistance to kidney decline, based on lab and animal studies — not people yet. It proposes that fixing this pathway could help protect kidneys, but no human trials are reported here.

Who did this work

Ceteraș LM · Brata VD · Dobrotă I · Borbei R · Clim M · Alexescu TG · Milaciu MV · Perne MG · Gerdanovics CA · Cozma A · Orășan OH

Source

Article · PubMed, the drug frontier · 2026 Aug 28
https://pubmed.ncbi.nlm.nih.gov/42737598/