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Serum uric acid variability and short-term mortality in chronic kidney disease: a retrospective cohort study with independent replication in MIMIC-IV

Paper C Peer reviewed Observational

Key takeaways

This study looked back at hospital records to see whether big swings in uric acid levels in the blood were tied to a higher risk of dying soon among people with chronic kidney disease. The researchers then checked their results in a second, separate records database called MIMIC-IV. We only have the title, so we cannot report how many people were included or how strong the link was. A study like this shows a link, not proof that uric acid swings cause death.

Who did this work

Fan Zhu (Central Hospital of Wuhan) · Wenyuan Gan (Central Hospital of Wuhan) · Wenli Chen (Central Hospital of Wuhan) · Xingruo Zeng (Central Hospital of Wuhan)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-09-16
https://doi.org/10.3389/fnut.2026.1919779