← brief for 2026-09-16 · Slowing decline

Histological grading of tertiary lymphoid structures correlates with renal impairment and adverse outcomes in ANCA-associated glomerulonephritis

Key takeaways

In ANCA vasculitis affecting the kidney, some biopsies contain small clusters of immune cells. This study graded those clusters and found that higher grades went along with worse kidney function and worse outcomes. It is an observational study, so it shows a link, not proof that the clusters cause the damage. The abstract was not available, so we cannot report how many patients were studied.

Who did this work

Yujia Wang (Fujian Medical University) · Kaiqi Huang (Fujian Medical University) · Jiaye Fang (Fujian Medical University) · Caiming Chen (Fujian Medical University) · Zigui Zheng (Fujian Medical University) · Xuan Tao (Fujian Medical University) · Jianxin Wan (Fujian Medical University) · Hong Chen (Fujian Medical University) · Huabin Ma (Fujian Medical University) · Yanfang Xu (Fujian Medical University)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-09-16
https://doi.org/10.3389/fimmu.2026.1916074