← brief for 2026-09-16 · Slowing decline

Ferroptosis as a target mechanism in heart and kidney disease

Paper D Peer reviewed Preclinical

Key takeaways

This review looks at ferroptosis, a type of cell death driven by iron that damages cells in the heart and kidneys. It gathers earlier research on whether blocking this process could protect those organs. That research comes mostly from animals and cells, not people yet. No treatment based on this idea has been proven in patients.

Who did this work

Simar Singh (University of Arizona) · Baljash Cheema (Northwestern University) · Hossein Ardehali (University of Arizona)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-09-14
https://doi.org/10.1172/jci202823