← brief for 2026-09-16 · Slowing decline

Exploring the mechanism of Yishen Huayu formula in intervening chronic kidney disease-mineral and bone disorder via the miR-340-5p/FGF-23/klotho signaling pathway.

Article D Peer reviewed Preclinical

Key takeaways

Researchers tested a traditional Chinese herbal mix called Yishen Huayu formula in rats with kidney damage. The rats had the bone and mineral problems that kidney disease can cause, called CKD-MBD. The team looked at how the herbs act on FGF-23 and klotho, two signals that control phosphate and bone health. This was in rats only, not people yet, and the part of the abstract we have does not give the results.

Who did this work

Zhao L · Liu W · Chen K · Xiao C · Zhang L · Chen G

Source

Article · PubMed, fibrosis reversal · 2026 Sep 15
https://pubmed.ncbi.nlm.nih.gov/42744042/