← brief for 2026-09-13 · Mind-body

Chronic kidney disease and cognitive decline: choroid plexus remodeling, glymphatic dysfunction, and alzheimer biomarker interpretation.

Key takeaways

This review found that people with chronic kidney disease often have cognitive problems and brain changes seen on scans, but the study only shows a link — not proof that kidney disease causes these brain changes. It combined many past studies and suggested the kidneys and brain may affect each other through blood flow, toxins, or scarring in brain tissue. No new data was collected; the authors called for more research to see if helping kidneys also helps thinking.

Who did this work

Corrêa LMA (Faculdade de Medicina de São José do Rio Preto (FAMERP), Avenida Brigadeiro Faria Lima, 5544, São José do Rio Preto, 15090-000, São Paulo, Brazil. [email protected].) · Oliveira da Silva R (Universidade Federal da Paraíba (UFPB), João Pessoa, Paraíba, Brazil.) · Brandão LKV (Centro Universitário Uninorte (UNINORTE), Rio Branco, Acre, Brazil.) · Delmiro Silva YR (Universidade Federal de Alagoas (UFAL), Arapiraca, Alagoas, Brazil.) · da Silva ÉVB (Universidade Federal de Pernambuco (UFPE), Recife, Pernambuco, Brazil.) · Tretow J (Far Eastern Federal University (FEFU), Vladivostok, Primorsky Krai, Russia.) · Gomes EDC (Universidade do Estado da Bahia (UNEB), Salvador, Bahia, Brazil.) · Fernandes CCS (Universidade do Estado da Bahia (UNEB), Salvador, Bahia, Brazil.) · Moreira GNCM (Escola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador, Bahia, Brazil.) · Zanella J (Universidade Federal de Santa Catarina (UFSC), Florianópolis, Santa Catarina, Brazil.)

Source

Paper · Europe PMC, CKD · 2026-09-11
https://doi.org/10.1007/s10072-026-09362-0