← brief for 2026-09-11 · Slowing decline

Protein mediators of chronic kidney disease in Type 2 diabetes: A mendelian randomization study.

Key takeaways

Kidney disease shows up in 20 to 50 percent of people with type 2 diabetes, and it is the top cause of kidney failure worldwide. Scientists used gene data from very large groups to find blood proteins that sit between diabetes and kidney damage, and flagged 71 of them. The method leans on genes people are born with, which is stronger than a plain survey, but it still shows a link rather than proof of cause. No one was given a treatment in this study.

Who did this work

Liang KYH · Zheng TM · Tan D · Sasako T · Ilboudo Y · Chen Y · Butler-Laporte G · Yoshiji S · Richards JB

Source

Article · PubMed, CKD progression and prevention · 2026 Sep 11
https://pubmed.ncbi.nlm.nih.gov/42726788/