← brief for 2026-09-11 · Slowing decline

Circulating Soluble Thrombomodulin Is Elevated in Early-Stage CKD and Is Associated with Renal Dysfunction: A Transcriptomic and Retrospective Cohort Study

Key takeaways

A study of people with early kidney disease found higher levels of a protein in the blood linked to worse kidney filtering rate (eGFR), but this only shows a connection — it does not prove the protein causes harm. The study included 1,240 adults and used existing medical records.

Who did this work

Jiao Wang (Huazhong University of Science and Technology) · Yongfen Xiong (Huazhong University of Science and Technology) · Chengyu Liu (Huazhong University of Science and Technology) · Shun Wang (Huazhong University of Science and Technology) · Wenli Wu (Huazhong University of Science and Technology)

Source

Paper · OpenAlex, CKD works · 2026-09-10
https://doi.org/10.3390/cells15181639