← brief for 2026-09-11 · Slowing decline

Blood pressure and cardiovascular risk in adults with non-proteinuric chronic kidney disease without diabetes.

Key takeaways

This Japanese study followed 287,238 adults with reduced kidney filtering rate (eGFR under 60) who had no diabetes and little or no protein in their urine. It compared blood pressure levels against later heart attacks, strokes, and other heart problems. Both high blood pressure and unusually low blood pressure tracked with more heart events in this group. The study watched what happened in real life rather than assigning treatment, so it shows a link, not proof that the blood pressure itself caused the harm.

Who did this work

Suzuki Y · Nishikawa M · Kaneko H · Okada A · Ko T · Fujiu K · Takeda N · Morita H · Nakagawa N · Azegami T · Hayashi K · Yokoo T

Source

Article · PubMed, CKD progression and prevention · 2026 Sep 10
https://pubmed.ncbi.nlm.nih.gov/42722733/