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Effects and potential mechanisms of astragaloside IV in animal models of renal fibrosis: a systematic review and meta-analysis.

Article D Peer reviewed Preclinical

Key takeaways

Researchers pooled results from many animal studies of astragaloside IV, a compound from the herb Astragalus, in kidney scarring. Scarring is the main way chronic kidney disease gets worse over time, and there are still very few treatments that target it. Across eight research databases, the compound protected animal kidneys and reduced scarring. This was all in animals, not people, so it is not a treatment anyone should take yet.

Who did this work

Li S · Zhang S · Cui L · Li Y · Wang Y · Wang Y

Source

Article · PubMed, CKD progression and prevention · 2026 Aug 25
https://pubmed.ncbi.nlm.nih.gov/42712548/