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Antihypertensive Pharmacotherapy in Chronic Kidney Disease: Integrating eGFR-Based Cutoffs, Mechanistic Insights, and Emerging Therapeutic Pathways.

Key takeaways

This is a review article, not a new study, so it reports no new results. It pulls together current advice on treating high blood pressure in people with chronic kidney disease, including which drugs to use at different levels of kidney filtering rate (eGFR). The authors note that newer drugs improve protein in the urine, kidney filtering rate over time, and heart outcomes. They also say it is hard to tell how much of that comes from lower blood pressure and how much from the drugs' other effects.

Who did this work

Sriperumbuduri S · Khan RW · Aftab S · Hiremath S · Dixon D · Gupta G

Source

Article · PubMed, Blood pressure targets on losartan/ARB · 2026 Sep 8
https://pubmed.ncbi.nlm.nih.gov/42712144/