← brief for 2026-09-07 · Slowing decline

Urinary Sclerostin and Renal Magnesium Handling in Proteinuric Non-Diabetic Chronic Kidney Disease.

Key takeaways

Sclerostin is a protein involved in the bone and mineral problems that come with kidney disease. Researchers measured it in the blood and urine of 70 adults who had kidney disease with protein leaking into the urine, and were not diabetic, at stages 1 through 5. They checked whether sclerostin levels tracked with how much magnesium the kidneys were dumping into the urine. All the measurements were taken at one point in time, so this can only show a link, not proof that one causes the other.

Who did this work

Wu CF · Kuo TH · Wu AB · Lin WH · Chao JY · Hung SY · Tseng CC · Liou HH · Wang MC

Source

Article · PubMed, CKD severity and reversal · 2026 Sep 7
https://pubmed.ncbi.nlm.nih.gov/42704754/