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Lactate-Mediated Lysine Lactylation in Renal Fibrosis: Current Progress and Challenges.

Key takeaways

This is a review article that pulls together other people's work, not a new study. It covers lactate, a waste product of burning sugar, and how it attaches to proteins in the kidney in a process called lactylation. The authors argue this tagging helps drive kidney scarring and could become a drug target. There are no new results, and no treatment based on this idea has been tested in people yet.

Who did this work

Wang W · Xu K · Xu Y · Ge X · Lv Y

Source

Article · PubMed, CKD progression · 2026 Sep 15
https://pubmed.ncbi.nlm.nih.gov/42703165/