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An integrative review of APOL1 kidney disease with a focus on the Brazilian population.

Key takeaways

This paper gathers earlier studies about APOL1, a gene that comes in versions linked to a higher risk of kidney disease. It looks at what those studies mean for people in Brazil, where many people have African ancestry and carry these gene versions. The underlying research is observational, so it shows a link between the gene and kidney disease, not proof that the gene alone causes it. This item arrived without an abstract, so no numbers from the review are available here.

Who did this work

Celia M Barbosa de Souza (Universidade Federal do Rio Grande do Sul) · Bibiana S de Oliveira Fam (Universidade Federal do Rio Grande do Sul) · Giovanna Câmara Giudicelli (Universidade Federal do Rio Grande do Sul) · Precil Diego Miranda de Menezes Neves (Hospital Alemão Oswaldo Cruz) · Francisco Veríssimo Veronese (Universidade Federal do Rio Grande do Sul) · Fernanda S Luiz Vianna (Universidade Federal do Rio Grande do Sul)

Source

Paper · OpenAlex, CKD works · 2026-09-05
https://doi.org/10.1016/j.clinsp.2026.101109