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Layered immune biomarker monitoring in IgA nephropathy: from mucosal IgA dysregulation to precision therapeutic response assessment

Key takeaways

IgA nephropathy is a kidney disease where an antibody called IgA builds up and damages the kidney's filters. This paper reviews blood and urine markers that doctors could track in layers, starting in the gut lining where the problem begins and ending at the kidney itself, to see whether a treatment is working. It is a review of work already published, not a new study, so it reports no results of its own. The idea is to match treatment to each person, but that approach has not been tested in a trial here.

Who did this work

Yuanyue Lu (Fifth Tianjin Central Hospital) · Changxi Sun (Fifth Tianjin Central Hospital) · Xiaoshuang Zhou (Shanxi Medical University)

Source

Paper · OpenAlex, CKD works · 2026-09-04
https://doi.org/10.3389/fmed.2026.1917560