← brief for 2026-09-05 · Nutrition & lifestyle

Effects of probiotic supplementation on disease progression in patients with moderate to severe chronic kidney disease: a randomized controlled trial.

Article B Peer reviewed Small trial

Key takeaways

This trial gave 72 people with stage 3 or 4 kidney disease either a probiotic (a live gut bacteria supplement) or a dummy pill. Nobody, not the patients and not the staff, knew who got which, which is the strongest way to run a small trial. The idea being tested is that gut bacteria feed into kidney damage. The posted abstract is cut off, so how long people were followed and what happened are not stated here, and a trial of 72 people is too small to settle whether probiotics slow kidney decline.

Who did this work

Saleh SE · Elnagar SSE · Fouda MA · Sayed-Ahmed N

Source

Article · PubMed, CKD progression · 2026 Sep 4
https://pubmed.ncbi.nlm.nih.gov/42697907/