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Doubly Robust Methods for Recurrent Event Outcomes: Causal Effects of Blood Pressure Medications on Acute Kidney Injuries

Key takeaways

This study looked at whether blood pressure medicines lead to sudden kidney injury, using health records rather than a trial. Sudden kidney injury means the kidneys stop filtering well over hours or days, and it can happen more than once to the same person. The authors used a statistical method built to handle repeat events and to reduce bias from records data. Because nobody was randomly assigned to a drug, this shows a link, not proof of cause.

Who did this work

W Zhang (Harvard University) · Cecilia A. Cotton (University of Waterloo) · Lan Wen (University of Waterloo)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-09-04
https://doi.org/10.1093/aje/kwag214