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Comparison of Standard (7–14 Days) versus Extended (>14 Days) Intravenous Antibiotic Treatment for Vesicoureteral Reflux-Associated Acute Pyelonephritis in Children: A Retrospective Cohort Study

Key takeaways

Doctors compared 7 to 14 days of IV antibiotics against more than 14 days for children with a kidney infection caused by urine flowing backward from the bladder. They looked back at old records instead of assigning treatment at random, so sicker children may have been given the longer course. That means this shows a link between treatment length and outcome, not proof that one length is better. It is also a preprint, so no outside experts have checked it yet.

Who did this work

Huimin Chen (Children's Hospital of Chongqing Medical University) · Mo Wang (Children's Hospital of Chongqing Medical University) · Gaofu Zhang (Children's Hospital of Chongqing Medical University)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-09-04
https://doi.org/10.21203/rs.3.rs-10772998/v1