← brief for 2026-09-03 · Slowing decline

RANDOMIZED CONTROLLED STUDY OF NEMOLIZUMAB IN PATIENTS WITH CHRONIC KIDNEY DISEASE AND ASSOCIATED PRURITUS: NIKAIA-1.

Article B Peer reviewed Small trial

Key takeaways

A drug called nemolizumab was tested against the severe itching that comes with kidney failure. It was a randomized trial: 258 people on dialysis got either the drug or a dummy shot every four weeks for 12 weeks. Itching is one of the hardest daily problems on dialysis, so a drug aimed straight at it matters. The published abstract stops before the actual numbers, so how well it worked is not yet clear here.

Who did this work

Mathur VS · Fishbane S · Ständer S · Szepietowski JC · Hernandez GT · Jamal A · Lynn R · Rossini M · Zhu J · Piketty C · Yosipovitch G

Source

Article · PubMed, Lifestyle and CKD · 2026 Sep 1
https://pubmed.ncbi.nlm.nih.gov/42680109/