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Post-translational protein S-palmitoylation in renal tubular injury: mechanisms and therapeutic implications

Key takeaways

This is a review of S-palmitoylation, a fatty tag that cells stick onto proteins to control where those proteins sit and what they do. It pulls together lab and animal findings suggesting the tagging goes wrong in injured kidney tubules, the tiny pipes that do the filtering. The authors argue this could become a drug target. It reports no new results and nothing has been tested in people.

Who did this work

Miao Li (Peking University) · Han Zhu (Jiangxi University of Traditional Chinese Medicine) · Huiping Zhao (Peking University) · Chenyang Liu (Center for Life Sciences) · Yan Wang (Peking University) · Li Zuo (Peking University)

Source

Paper · OpenAlex, CKD works · 2026-09-01
https://doi.org/10.3389/fcell.2026.1960988