← brief for 2026-09-03 · Slowing decline

Integrated Serum Lipidomics, Renal Transcriptomics, and Mendelian Randomization Reveal Glycerophospholipid Dysregulation in Calcium Oxalate Kidney Stones

Key takeaways

Researchers compared fat molecules in the blood and gene activity in kidney tissue in people with calcium oxalate kidney stones. They found a pattern of disturbed fats, and used a genetics method to test whether that pattern comes before the stones. This shows a link, not proof of cause. It is a preprint, so no other scientists have checked it yet.

Who did this work

Bo Tao (Kunming University of Science and Technology) · Zhangxiao Xu (Kunming University of Science and Technology) · Yuanjian Niu (Kunming University of Science and Technology) · Yuan Zhao (Kunming University of Science and Technology) · Limin Shi (Kunming University of Science and Technology) · Zhengwei Zhao (Kunming University of Science and Technology) · Lijun Wang (Kunming University of Science and Technology)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-09-02
https://doi.org/10.21203/rs.3.rs-10677612/v1