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Glycemic assessment when hemoglobin A1c is unreliable: a clinical-laboratory framework for kidney disease, anemia, and hemoglobinopathies

Key takeaways

The A1c blood test is meant to show average blood sugar over roughly three months, but it can read wrong in people with kidney disease, low red blood cell counts, or inherited blood disorders. This paper lays out a step by step guide for doctors on when to distrust A1c and what to use instead, such as sensor glucose readings or other blood markers. It is practical guidance built from earlier work, not a new study, so there are no results.

Who did this work

Tianqiang Wu (Zhejiang Chinese Medical University) · Zihan Guan (Zhejiang Chinese Medical University) · Wenpin Cai (Zhejiang Chinese Medical University)

Source

Paper · OpenAlex, CKD works · 2026-09-01
https://doi.org/10.3389/fendo.2026.1898713