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Extracellular cold-inducible RNA-binding protein in renal ischemia–reperfusion injury and its progression to chronic kidney disease

Key takeaways

This paper reviews what is known about a protein called eCIRP, which cells release when blood flow to the kidney is cut off and then restored. That kind of injury can later turn into long term kidney disease. The article pulls together earlier lab work and suggests the protein as a target worth studying. It presents no new results and has not been tested as a treatment in people.

Who did this work

Max Brenner (Feinstein Institute for Medical Research) · Ping Wang (Feinstein Institute for Medical Research)

Source

Paper · OpenAlex, CKD works · 2026-09-02
https://doi.org/10.1186/s10020-026-01628-9