← brief for 2026-09-03 · Nutrition & lifestyle

Body composition phenotypes are key predictors of cardiovascular-kidney-metabolic multimorbidity and long-term mortality: insights from a population-based cohort study

Key takeaways

This study followed a large group of adults from the general population over many years. It sorted them by body composition, meaning how much fat and muscle they carry and where it sits, and then tracked who developed heart, kidney and metabolic disease together. People with the worst body composition patterns had more of this combined illness and a higher chance of dying during follow-up. It is an observational study, so it shows a link, not proof that body composition causes the disease.

Who did this work

Gwyneth Kong (National University Hospital) · Made Ayu Utami Intaran (National University of Singapore) · Ernest Su Wei Soh (National University of Singapore) · Yalkin Yazicioglu (National University of Singapore) · Rachel Goh (National University of Singapore) · Srinithy Nagarajan (National University of Singapore) · Jiong‐Wei Wang (National University of Singapore) · Xin Zhou (Wenzhou Medical University) · Xiaodong Zhou (Wenzhou Medical University) · Ming-Hua Zheng (Wenzhou Medical University) · Mark Y. Chan (National University of Singapore) · Anurag Mehta (Emory University)

Source

Paper · OpenAlex, CKD works · 2026-09-02
https://doi.org/10.1007/s00392-026-03010-5