← brief for 2026-09-01 · Slowing decline

Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus

Trial No results yet Not peer reviewed

Key takeaways

Many people on dialysis get severe itchy skin, which is hard to live with. Difelikefalin is a drug that has already been shown to reduce that itching in adults on dialysis. This trial tests whether it is safe and tolerable in teenagers aged 12 to 17 on dialysis. It is a study that is starting, so there are no results yet.

Who did this work

Run by Vifor Fresenius Medical Care Renal Pharma.
Sites: Sichuan University-West China Second University Hospital · The First Affiliated Hospital, Sun Yat-sen University · Guangzhou Women and Children's Medical Center · The Children's Hospital Zhejiang University School of Medicine · The Children's Hospital of Fudan University · Huazhong University of Science and Technology-Tongji Medical College-The Central Hospital of Wuhan

Source

Trial · ClinicalTrials.gov, CKD recruiting · 2026-09-01
https://clinicaltrials.gov/study/NCT06593392