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← brief for 2026-09-01 · Transplant & xeno

Protective Effects of Quercetin and Sucrose on Cold Preservation Injury in Porcine Kidneys Donated After Cardiac Death.

Article D Peer reviewed Preclinical

Key takeaways

Researchers added quercetin, an antioxidant found in fruit and vegetables, plus sucrose (table sugar) to the cold fluid used to store donated kidneys. They tested it in pig kidneys taken after the heart stopped, against the standard storage fluid, to see if it reduced the damage that happens when blood flow returns. This was done in pigs, not people, so it is early work. If it holds up, it could make more donated kidneys good enough to transplant.

Who did this work

Ishii D · Toriumi A · Obara H · Satake Y · Okada Y · Dewa H · Imamura M · Matsuno N

Source

Article · PubMed, Climate, heat and the kidney · 2026 Sep 1
https://pubmed.ncbi.nlm.nih.gov/42675830/