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Nephropathies Associated with Sickle Cell Trait and How to Study Them.

Key takeaways

People with sickle cell trait — just one copy of the gene, not full disease — may have worse kidney filtering rate over time and more protein in their urine, based on studies of large groups. This shows a link between the trait and kidney problems, but it does not prove the trait causes them. More research is needed to understand why and how often this happens.

Who did this work

Williams AC · Sheehan VA · Hong AL

Source

Article · PubMed, CKD progression and prevention · 2026 Sep 1
https://pubmed.ncbi.nlm.nih.gov/42678789/