← brief for 2026-09-01 · Regeneration & devices

Heat shock protein 70 protects against peroxynitrite-induced inactivation of the cardiac sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA2a).

Key takeaways

In test-tube experiments with human kidney cells, a protein called Hsp70 helped protect another protein that moves calcium in and out of cells — a process important for healthy kidney function. This was not tested in people or animals, so it is too early to say if this helps kidneys in real patients.

Who did this work

Vigna C · Fu M · Humaid A · Tupling AR

Source

Article · PubMed, Climate, heat and the kidney · 2026 Sep 1
https://pubmed.ncbi.nlm.nih.gov/42678724/