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Assessment of NGAL, eGFR, and tubular injury markers for early detection of chemotherapy-induced nephrotoxicity in pediatric oncology patients

Paper C Peer reviewed Observational

Key takeaways

Doctors checked whether blood and urine markers can catch kidney damage from cancer drugs early in children being treated for cancer. They compared NGAL, a protein that rises when kidney tubules are hurt, against the usual kidney filtering rate estimate (eGFR) and other injury markers. This was an observational study, so it can show which markers move first, not prove that acting on them protects kidneys. The full abstract was not posted, so the number of children and the exact accuracy figures are not available.

Who did this work

Petya Markova (Medical University Plovdiv) · Antoniya Yaneva (Medical University Plovdiv) · Mariya Spasova (Medical University Plovdiv) · Stoyan Markov (St. George's University) · Kostadin Kostadinov (Medical University Plovdiv)

Source

Paper · OpenAlex, CKD works · 2026-08-31
https://doi.org/10.3897/folmed.68.e184913