← brief for 2026-09-01 · Slowing decline

A case report of WT1-associated infantile steroid-resistant nephrotic syndrome with atypical genotype–phenotype correlation

Key takeaways

This is a report on a single infant with nephrotic syndrome, a condition where the kidneys leak large amounts of protein into the urine, caused by a change in the WT1 gene. Steroid-resistant means the usual steroid treatment did not work. The gene change did not cause the illness pattern doctors expected, which is why the case was written up. One patient cannot show cause or tell you what will happen in anyone else.

Who did this work

Alejandra Rebolledo Zamora (Hospital del Niño) · Laura Edith González Rodríguez (Hospital del Niño) · Irais Fátima Sierra Pineda (Hospital del Niño) · Ma. Fabiola Del Carmen Lara Hernandez (Hospital del Niño) · Sofía Pasquel Sentíes (Hospital del Niño) · José María Ortega Solar (Hospital del Niño)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-08-31
https://doi.org/10.1007/s44571-026-00004-6