← brief for 2026-08-31 · Regeneration & devices

Podocyte injury damages podocytes in chimeric organoids.

Key takeaways

In test-tube kidney organoids made from mouse cells, damaging some filtering cells caused nearby healthy ones to get hurt too — even without direct contact. This suggests a signal passes between cells during injury, but the finding has not been tested in people yet.

Who did this work

Udagawa T · Araoka T · Osafune K · Matsusaka T

Source

Article · PubMed, organoids & devices · 2026 Aug 31
https://pubmed.ncbi.nlm.nih.gov/42672065/